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Pharmaceutical Immunology

Our group performs research at the crossroads of immunology and vascular biology. A major focus of our research lies on investigating inflammation-induced changes of lymphatic vessels and their impact on leukocyte migration. Furthermore, we are investigating how chronic inflammation affects lymphatic vessel function and the induction of adaptive immunity in draining lymph nodes. An important goal of our research is to identify and validate new molecules, which could serve as therapeutic targets to modulate immune responses.

Awards & Achievements

ETH Zurich news: Shortcut for dendritic cells

Riccardo Montecchi receives the "Best Speaker Award" at the SSMVR (Swiss Society of Microcirculation and Vascular Research) meeting in Interlaken, December 3, 2021

Venture Kick: Startup developing a novel antibody-based therapy for corneal transplant rejection win CHF 10'000:

external pageEMUNA Therapeutics: a novel antibody-based therapy for corneal transplant rejection (Morgan Hunter, Aline Bauer, Cornelia Halin Winter)

Publications

Reviews

external pageLeukocyte Trafficking in Lymphatic Vessels.
Bauer A, Tatliadim H, Halin C. (2022) Cold Spring Harb Perspect Med doi: 10.1101/cshperspect.a041186

external pageImaging leukocyte migration through afferent lymphatics
Collado-Diaz V, Medina-Sanchez JD, Gkountidi AO, Halin C. Immunol Rev. 2021 Oct 27. doi: 10.1111/imr.13030. Online ahead of print.

external pageStructure and Immune Function of Afferent Lymphatics and Their Mechanistic Contribution to Dendritic Cell and T Cell Trafficking
Arasa J, Collado-Diaz V, Halin C. Cells. 2021 May 20;10(5):1269. doi: 10.3390/cells10051269. PMID: 34065513 Free PMC article. Review.

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