Cancer microenvironment

The advent of immune checkpoint inhibition therapies has fundamentally changed the care pathway of cancer patients giving hope for cure in previously deadly diseases. Despite this, a considerable portion of patients do not benefit from these treatments and we need to understand better the complex interplay between immune cells and cancer cells to offer better treatment solutions. In this project, we investigate the complexity of cancer microenvironment from the perspective of patient survival in both, an untreated setting as well as in the context of response to therapies.

Multiplexed immunofluorescence image of lung cancer tissue visualising tumor cells (white) and different infiltrating immune cells
Multiplexed immunofluorescence image of lung cancer tissue visualising tumor cells (white) and different infiltrating immune cells
Map of different regions in lung cancer and individual cells within generated by machine learning algorithms
Map of different regions in lung cancer and individual cells within generated by machine learning algorithms
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